About Clemson University. Clemson University in Clemson, SC reports an overall acceptance rate of 38.3%, an early-round acceptance rate of 35.7%, an SAT middle 50% of 1250–1410, a class size of 4,880, and a yield of 20.0% based on the most recent Common Data Set filings. Top-ranked public university in South Carolina. Strong engineering, business, and agriculture programs. Competitive admissions (38% rate) with robust school spirit and SEC athletics.